Science always evolves, responding to its leading challenges as they change through history. After centuries of triumph and optimism, science is now called on to remedy the pathologies of the global industrial system of which it forms the basis. Whereas science was previously understood as steadily advancing in the certainty of our knowledge nd control of the natural world, now science is seen as coping with many uncertainties in policy issues of risk and the environment. In response, new styles of scientific activity are being developed. The reductionist, analytical worldview which divides systems into ever smaller elements, studied by ever more esoteric specialism, is being replaced by a systemic, synthetic and humanistic approach. The old dichotomies of facts and values, and of knowledge and ignorance, are being transcended. Natural systems are recognized as dynamic and complex; those involving interactions with humanity are ‘emergent', including properties of reflection and contradiction. The science appropriate to this new condition will be based on the assumptions of unpredictability, incomplete control, and a plurality of legitimate perspectives.

Silvio 0. Funtowicz and Jerome R. Ravetz, "Science for the post-normal Age" (1993)